Increasingly, families are refusing to allow their loved ones' organs to help save other people's lives after their death.
SSIM (Structural Similarity Index Measure) compares two images by evaluating luminance, contrast, and structural patterns across local windows. It returns a score from -1 to 1: 1.0 means the images are pixel-identical, 0 means no structural correlation, and negative values mean the images are anti-correlated (less alike than random noise). For glyph comparison, it answers the question: do these two rendered characters share the same visual structure?
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Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10142-1