Again, the answer to this question varies from company to company. And again, testing is the way to find out what works best. Typically, weekends and mornings seem to be times when multiple emails are opened, but since your audience may have different habits, it's best to experiment and then use your data to decide.
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This is a complicated technical and social problem, with no single solution. We also have competing priorities for what is the most important problem with WebAssembly to fix first.
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